Endocrine Abstracts

Introduction: Nutrition is considered to be one of the main environmental factors influencing the outcome of pregnancy, the child’s development and the mother’s health (2). Given that this period is characterised by profound physiological changes (15), motherhood is a stage of psychic reorganisation due to the major bodily transformations that reactivate their bodily preoccupations (16), evoking a difficulty in adapting to their new bodies, which may expose pregnant ...

Introduction: Endocrine hypertension is the most common cause of secondary hypertension affecting nearly 3% of the population. Adrenal etiologies play a significant role in these cases. An adrenal incidentaloma is an asymptomatic adrenal tumor, at least one cm in diameter, discovered incidentally during a medical imaging examination. It requires an investigation into its secretory or malignant nature leading to the development of arterial hypertension.Ma...

Introduction: Several studies have incriminated hypomagnesemia in the pathophysiology of diabetes, as the prevalence of this deficit in type 2 diabetics is high, and as it is correlated with glycemic control and chronic diabetic complications.Aims: Studying the prevalence of hypomagnesemia in type 2 diabetics and assessing its impact on quality of life, glycemic control and chronic diabetic complications. Patients and methods: We conducted a descriptive ...

Introduction: Verneuil’s disease, also known as Hidradenitis suppurativa, is a chronic inflammatory dermatosis characterized by recurrent episodes. It’s manifested by painful deep inflammatory nodules, comedones, and scarring in areas rich in apocrine glands. Its prevalence is estimated at 1% of the population. It is influenced by factors such as obesity, smoking, and genetics. We report the case of a patient admitted for diabetes in whom Hidradenitis suppurativa was...

Introduction: Growth hormone deficiency (GHD) is a rare cause of growth retardation whose diagnosis remains relatively late. Its etiologies are multiple, and its treatment could improve the stature prognosis of the children. The objective of this study was to describe the clinical, biological, radiological, and therapeutic characteristics of GHD, and its outcomes after treatment.Methods: A cross-sectional study was conducted in the Endocrinology departme...

Introduction: Macroprolactinemia is a polymeric form of prolactin release that leads to clinically paucisymptomatic presentations. It can be isolated or associated with other causes of hyperprolactinemia. We report the case of macroprolactinemia discovered in a patient being treated for an empty sella turcica.Case report: This concerns a 47-year-old patient, monitored since the age of 31 for moderate idiopathic hyperprolactinemia discovered following bil...

Introduction: Schmidt’s syndrome also known as autoimmune polyglandular syndrome type 2 (APS type 2) is a rare endocrine disorder defined by the combined occurrence of Addison disease with autoimmune thyroid disease. The rarity of the condition and the atypical presentation of adrenal insufficiency and hypothyroidism often lead to misdiagnosis with life-threatening consequences for the patient. In this study we report an exhaustive monocentric analysis of 22 patients diag...

Introduction: Chromosomal abnormality 47, XYY, despite being present in approximately 1 in 1000 newborn boys, remains less known phenotypically and more than 85% of men are never diagnosed. Males with 47, XYY syndrome are described to be phenotypically normal. They present often a developmental delay, behavioral difficulties and learning disabilities that may be associated with accelerated growth rate and taller stature in adulthood. Endocrine disorders, especially pubertal de...

Introduction: Moyamoya disease is a rare angiopathy characterized by a progressive stenosis of the intracranial internal carotid arteries (ICA). First described in 1957, its pathophysiological mechanisms are still not well understood. Its association with various systemic diseases is termed moyamoya syndromeObservation: A 21-year-old female patient, with a family history of hypothyroidism, was admitted initially with stroke. The clinical examination reve...

Introduction: Klinefelter syndrome is the most prevalent male chromosomal disorder, characterized by the presence of additional X chromosomes. Most males with Klinefelter syndrome have 47, XXY and normal intelligence. Intellectual disability occurs in males with Klinefelter syndrome variants, who have a higher number of X chromosomes. Here we report a rare case of a 49, XXXXY syndrome revealed by intellectual deficit and pubertal delay.Observation: An 18...